Tg(KLK3-cre)13Saa
Transgene Detail

Summary

• Symbol: Tg(KLK3-cre)13Saa
• Name: transgene insertion 13, Sarki A Abdulkadir
• MGI ID: MGI:2447387
• Synonyms: PSA-Cre
• Transgene: Tg(KLK3-cre)13Saa Location: unknown
• Alliance: Tg(KLK3-cre)13Saa page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(KLK3-cre)13Saa expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  KLK3 (354)

  Klk1	(MGI:102850)
  Klk1b1	(MGI:892019)
  Klk1b3	(MGI:97322)
  Klk1b4	(MGI:97320)
  Klk1b5	(MGI:892020)
  Klk1b8	(MGI:892018)
  Klk1b9	(MGI:95293)
  Klk1b11	(MGI:892023)
  Klk1b16	(MGI:891982)
  Klk1b21	(MGI:892022)
  Klk1b22	(MGI:95291)
  Klk1b24	(MGI:892021)
  Klk1b26	(MGI:891981)
  Klk1b27	(MGI:891980)

• Mutation details: 6 kb of human KLK3 promoter sequences was used to drive cre expression in the mouse prostate. The KLK3 promoter is active after puberty. (J:74350)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	KLK3 (human) Summary of all recombinase alleles driven by KLK3. Comparative matrix view of recombinase activities Alliance human KLK3 gene page

Disease models

Tumor Data

List all tumor models in MMHCdb carrying Tg(KLK3-cre)13Saa

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:74350 Abdulkadir SA, et al., Conditional loss of nkx3.1 in adult mice induces prostatic intraepithelial neoplasia. Mol Cell Biol. 2002 Mar;22(5):1495-503
• All: 4 reference(s)