Sod2^tm1Shs
Targeted Allele Detail

Summary

• Symbol: Sod2^tm1Shs
• Name: superoxide dismutase 2, mitochondrial; targeted mutation 1, Takuji Shirasawa
• MGI ID: MGI:2447406
• Synonyms: MnSOD^lox, SOD2^f
• Gene: Sod2 Location: Chr17:13226726-13237006 bp, + strand Genetic Position: Chr17, 8.75 cM
• Alliance: Sod2^tm1Shs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:78889
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 3 was flanked with a floxed neomycin resistance cassette and a single loxP site via homologous recombination. (J:78889)

Disease models

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	10 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Sod2^tm1Shs

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sod2 Mutation: 26 strains or lines available

References

• Original: J:78889 Ikegami T, et al., Model mice for tissue-specific deletion of the manganese superoxide dismutase (MnSOD) gene. Biochem Biophys Res Commun. 2002 Aug 23;296(3):729-36
• All: 34 reference(s)