Tg(DMRT1-cre)1Svs
Transgene Detail

Summary

• Symbol: Tg(DMRT1-cre)1Svs
• Name: transgene insertion 1, David W Silversides
• MGI ID: MGI:2447637
• Synonyms: pDMRT1p-Cre
• Transgene: Tg(DMRT1-cre)1Svs Location: unknown
• Alliance: Tg(DMRT1-cre)1Svs page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(DMRT1-cre)1Svs expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  pig, domestic	DMRT1

• Mutation details: 2.6 kb of pig DMRT1 5' flanking sequences were used to express the cre recombinase gene in embryonic germ cells. Transgene expression in germ cells was confirmed by mating transgenic animals to a YFP reporter line and observing fluorescence in fetal ovaries and testicular cords. (J:80695)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	DMRT1 (pig, domestic) Summary of all recombinase alleles driven by DMRT1. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Two transgenic lines were established, lines 1 and 2B.

References

• Original: J:80695 Boyer A, et al., Conservation of the function of DMRT1 regulatory sequences in mammalian sex differentiation. Genesis. 2002 Dec;34(4):236-43
• All: 3 reference(s)