Tg(KRT14-cre/PGR)1Der
Transgene Detail

Summary

• Symbol: Tg(KRT14-cre/PGR)1Der
• Name: transgene insertion 1, Dennis R Roop
• MGI ID: MGI:2447651
• Synonyms: K14.CrePR1
• Transgene: Tg(KRT14-cre/PGR)1Der Location: unknown
• Alliance: Tg(KRT14-cre/PGR)1Der page

Transgene origin

• Strain of Origin: (ICR x FVB)F1

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: mifepristone
• Mutation: Insertion
• Tg(KRT14-cre/PGR)1Der expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  KRT14 (3861)

  Krt14

  (MGI:96688)

• Mutation details: This transgene expresses a Cre recombinase and human progesterone receptor gene fusion under the control of a human keratin 14 promoter. This promoter drives the expression of Cre recombinase in the basal layer of the epidermis and hair follicles. (J:69320)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	KRT14 (human) Summary of all recombinase alleles driven by KRT14. Comparative matrix view of recombinase activities Alliance human KRT14 gene page

Disease models

Tumor Data

List all tumor models in MMHCdb carrying Tg(KRT14-cre/PGR)1Der

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:69320 Berton TR, et al., Characterization of an inducible, epidermal-specific knockout system: differential expression of lacZ in different Cre reporter mouse strains. Genesis. 2000 Feb;26(2):160-1
• All: 15 reference(s)