Tg(Wnt1-cre/Esr1*)10Rth
Transgene Detail

Summary

• Symbol: Tg(Wnt1-cre/Esr1*)10Rth
• Name: transgene insertion 10, David H Rowitch
• MGI ID: MGI:2447684
• Synonyms: Tg(Wnt1-cre/Esr1)10Rth
• Transgene: Tg(Wnt1-cre/Esr1*)10Rth Location: unknown
• Alliance: Tg(Wnt1-cre/Esr1*)10Rth page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Wnt1-cre/Esr1*)10Rth expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Wnt1

• Mutation details: This transgene expresses a tamoxifen-inducible form of a Cre recombinase/estrogen receptor fusion protein. The Wnt1 regulatory sequences initially direct expression in the midbrain. After neural tube closure, expression occurs in the dorsal and ventral midlines of the midbrain and caudal diencephalon, the midbrain-hindbrain junction and in the dorsal spinal cord. (J:69326)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Wnt1 (species not specified) Summary of all recombinase alleles driven by Wnt1. Comparative matrix view of recombinase activities

Expression

In Mice Carrying this Mutation:

19 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:69326 Danielian PS, et al., Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase. Curr Biol. 1998 Dec 3;8(24):1323-6
• All: 11 reference(s)