Tg(rtetR-tetO-cre)1Mhz
Transgene Detail

Summary

• Symbol: Tg(rtetR-tetO-cre)1Mhz
• Name: transgene insertion 1, Martin Holzenberger
• MGI ID: MGI:2447693
• Synonyms: DAI-Cre
• Transgene: Tg(rtetR-tetO-cre)1Mhz Location: unknown
• Alliance: Tg(rtetR-tetO-cre)1Mhz page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(rtetR-tetO-cre)1Mhz expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  bacteria	tetO

• Mutation details: Upon induction with doxycycline, this transgene expresses both the rtTA activator and Cre recombinase from a bidirectional doxycycline responsive promoter (tetO) in most tissues. (J:69328)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	tetO (bacteria) Summary of all recombinase alleles driven by tetO.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:69328 Holzenberger M, et al., Ubiquitous postnatal LoxP recombination using a doxycycline auto-inducible Cre transgene (DAI-Cre). Genesis. 2000 Feb;26(2):157-9
• All: 1 reference(s)