Tg(Mpz)80.3Wra
Transgene Detail

Summary

• Symbol: Tg(Mpz)80.3Wra
• Name: transgene insertion 80.3, Lawrence Wrabetz
• MGI ID: MGI:2447696
• Synonyms: Tg80.3
• Transgene: Tg(Mpz)80.3Wra Location: unknown
• Alliance: Tg(Mpz)80.3Wra page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Mpz)80.3Wra expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mpz (MGI:103177)

• Mutation details: The entire Mpz gene (including 6 kb of promoter sequences, all exons and introns, and the natural polyadenylation signal) was used as the transgene. Transgenic line 80.3 carries 2 copies of the integrated transgene. Transgene expression is approximately 0.3-fold that of the endogenous protein. (J:78758)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:78758 Wrabetz L, et al., P(0) glycoprotein overexpression causes congenital hypomyelination of peripheral nerves. J Cell Biol. 2000 Mar 6;148(5):1021-34
• All: 1 reference(s)