Nrg1^tm3Cbm
Targeted Allele Detail

Summary

• Symbol: Nrg1^tm3Cbm
• Name: neuregulin 1; targeted mutation 3, Carmen Birchmeier
• MGI ID: MGI:2447761
• Synonyms: nrg-1^f, nrg-1^flox
• Gene: Nrg1 Location: Chr8:32299493-33381858 bp, - strand Genetic Position: Chr8, 18.75 cM
• Alliance: Nrg1^tm3Cbm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:69623
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• A floxed allele was generated that contained loxP sites inserted into intron 6 and in intron 9. (J:69623)

Expression

In Mice Carrying this Mutation:

4 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nrg1 Mutation: 54 strains or lines available

References

• Original: J:69623 Yang X, et al., Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation. Neuron. 2001 May;30(2):399-410
• All: 22 reference(s)