Lin7atm1Dsb
Targeted Allele Detail
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| Symbol: |
Lin7atm1Dsb |
| Name: |
lin-7 homolog A, crumbs cell polarity complex component; targeted mutation 1, David S Bredt |
| MGI ID: |
MGI:2447803 |
| Synonyms: |
MALS-1 KO |
| Gene: |
Lin7a Location: Chr10:107107547-107257335 bp, + strand Genetic Position: Chr10, 55.83 cM
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| Alliance: |
Lin7atm1Dsb page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:68187
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| Parent Cell Line: |
JM-1 (ES Cell)
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| Strain of Origin: |
129X1/SvJ
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exon 2 was replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region encoded 39 amino acids. Western blot analysis of brain homogenates indicated an absence of protein in homozygous mutant mice.
(J:68187)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Lin7a Mutation: |
23 strains or lines available
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| Original: |
J:68187 Misawa H, et al., Contrasting localizations of mals/lin-7 pdz proteins in brain and molecular compensation in knockout mice. J Biol Chem. 2001 Mar 23;276(12):9264-72 |
| All: |
4 reference(s) |
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Analysis Tools
