Isl2^tm1Arbr
Targeted Allele Detail

Summary

• Symbol: Isl2^tm1Arbr
• Name: insulin related protein 2 (islet 2); targeted mutation 1, Sylvia Arber
• MGI ID: MGI:2447837
• Synonyms: Isl2^DTA
• Gene: Isl2 Location: Chr9:55445956-55453464 bp, + strand Genetic Position: Chr9, 30.13 cM, cytoband C
• Alliance: Isl2^tm1Arbr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:69623
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: An IRES-loxP-stop-loxP-DTA (diphtheria toxin) cassette was inserted into the sequences encoding the 3'UTR of the gene. (J:69623)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Isl2 Mutation: 28 strains or lines available

References

• Original: J:69623 Yang X, et al., Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation. Neuron. 2001 May;30(2):399-410
• All: 16 reference(s)