Igf2r^tm1Rlj
Targeted Allele Detail

Summary

• Symbol: Igf2r^tm1Rlj
• Name: insulin-like growth factor 2 receptor; targeted mutation 1, Randy L Jirtle
• MGI ID: MGI:2447856
• Synonyms: M6PR flox
• Gene: Igf2r Location: Chr17:12901293-12988551 bp, - strand Genetic Position: Chr17, 8.64 cM, cytoband A-C
• Alliance: Igf2r^tm1Rlj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:80932
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 10 was left flanked by single loxP sites after the excision of a floxed selection cassette in vitro. (J:80932)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igf2r Mutation: 99 strains or lines available

References

• Original: J:80932 Wylie AA, et al., Tissue-specific inactivation of murine M6P/IGF2R. Am J Pathol. 2003 Jan;162(1):321-8
• All: 8 reference(s)