Ccr8^tm1Vnk
Targeted Allele Detail

Summary

• Symbol: Ccr8^tm1Vnk
• Name: C-C motif chemokine receptor 8; targeted mutation 1, Chandrasekar Venkataraman
• MGI ID: MGI:2447885
• Synonyms: CCR8^-
• Gene: Ccr8 Location: Chr9:119921199-119923972 bp, + strand Genetic Position: Chr9, 71.39 cM, cytoband F4
• Alliance: Ccr8^tm1Vnk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:80898
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The gene was disrupted by replacement of the first 178 bp of coding sequences and 46 bp of upstream non-coding sequences with an IRES-lacZ-neo cassette via homologous recombination. Absence of gene expression in homozygous mutant animals was confirmed by RT-PCR analysis of thymus RNA. (J:80898)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccr8 Mutation: 41 strains or lines available

References

• Original: J:80898 Chung CD, et al., CCR8 Is Not Essential for the Development of Inflammation in a Mouse Model of Allergic Airway Disease. J Immunol. 2003 Jan 1;170(1):581-7
• All: 1 reference(s)