Tg(CKMM-tTA)A3Rhvh
Transgene Detail

Summary

• Symbol: Tg(CKMM-tTA)A3Rhvh
• Name: transgene insertion A3, R Hooft van Huijsduijnen
• MGI ID: MGI:2448088
• Synonyms: MCK-tTA, Pmck-tTA
• Transgene: Tg(CKMM-tTA)A3Rhvh Location: unknown
• Alliance: Tg(CKMM-tTA)A3Rhvh page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: Sequence encoding the tTA transactivator was placed under the control of the human creatine kinase, muscle promoter, which drove strong expression in striated muscle and weak expression in heart and lung tissue. (J:81109)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:81109 Ghersa P, et al., Highly controlled gene expression using combinations of a tissue-specific promoter, recombinant adenovirus and a tetracycline-regulatable transcription factor. Gene Ther. 1998 Sep;5(9):1213-20
• All: 18 reference(s)