Prmt1^{Gt(U3BetaGeo)7.4.2Rul}
Gene trapped Allele Detail

Summary

• Symbol: Prmt1^{Gt(U3BetaGeo)7.4.2Rul}
• Name: protein arginine N-methyltransferase 1; gene trap 7.4.2 H Earl Ruley
• MGI ID: MGI:2448365
• Synonyms: 7.4.2, Prmt1 -
• Gene: Prmt1 Location: Chr7:44626179-44635844 bp, - strand Genetic Position: Chr7, 29.07 cM
• Alliance: Prmt1^{Gt(U3BetaGeo)7.4.2Rul} page

Mutation origin

• Mutant Cell Line: 7.4.2
• Germline Transmission: Earliest citation of germline transmission: J:61432
• Parent Cell Line: D3H (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: U3betageo Vector Type: gene trap
• Mutation details: The gene trap vector inserted into an intron of the gene. A beta-galactosidase fusion protein is expressed from this allele under the control of the endogenous promoter. (J:61432, J:151684)

Expression

In Mice Carrying this Mutation:	26 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prmt1 Mutation: 35 strains or lines available

References

• Original: J:61432 Pawlak MR, et al., Arginine N-methyltransferase 1 is required for early postimplantation mouse development, but cells deficient in the enzyme are viable. Mol Cell Biol. 2000 Jul;20(13):4859-69
• All: 2 reference(s)