Dach1^tm1Krs
Targeted Allele Detail

Summary

• Symbol: Dach1^tm1Krs
• Name: dachshund family transcription factor 1; targeted mutation 1, Stefan Krauss
• MGI ID: MGI:2448366
• Gene: Dach1 Location: Chr14:98024289-98407201 bp, - strand Genetic Position: Chr14, 48.25 cM, cytoband E3
• Alliance: Dach1^tm1Krs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:81143
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1, which contains the start codon, was replaced with a neomycin cassette inserted by homologous recombination. Transcript was undetected in homozygous mutant embryos by in situ hybridization. (J:81143)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dach1 Mutation: 51 strains or lines available

References

• Original: J:81143 Backman M, et al., Targeted disruption of mouse Dach1 results in postnatal lethality. Dev Dyn. 2003 Jan;226(1):139-44
• All: 3 reference(s)