Foxi1^tm1Sven
Targeted Allele Detail

Summary

• Symbol: Foxi1^tm1Sven
• Name: forkhead box I1; targeted mutation 1, Sven Enerback
• MGI ID: MGI:2448634
• Synonyms: Fkh10^-
• Gene: Foxi1 Location: Chr11:34154341-34158089 bp, - strand Genetic Position: Chr11, 19.65 cM, cytoband A5
• Alliance: Foxi1^tm1Sven page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:51291
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The gene was disrupted by replacement of the forkhead domain-encoding exon with a PGK-neo cassette via homologous recombination. (J:51291)

Disease models

Expression

In Structures Affected by this Mutation:

17 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Foxi1 Mutation: 18 strains or lines available

References

• Original: J:51291 Hulander M, et al., The winged helix transcription factor Fkh10 is required for normal development of the inner ear. Nat Genet. 1998 Dec;20(4):374-6
• All: 9 reference(s)