Tg(Pbsn-FGF7)3293Ng
Transgene Detail

Summary

• Symbol: Tg(Pbsn-FGF7)3293Ng
• Name: transgene insertion 3293, Norman M Greenberg
• MGI ID: MGI:2448654
• Synonyms: PKS
• Transgene: Tg(Pbsn-FGF7)3293Ng Location: unknown
• Alliance: Tg(Pbsn-FGF7)3293Ng page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Pbsn-FGF7)3293Ng expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  FGF7 (2252)

  Fgf7	(MGI:95521)

• Mutation details: The transgene consists of a rat Pbsn minimal promoter and a human FGF7 cDNA. The rat probasin minimal promoter (-426 to +28) was used to drive transgene expression in prostate epithelium. Four lines were established: 3258, 3293, 3295, and 3298. (J:80821)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Four transgenic lines (3258, 3293, 3295, and 3298) were created.

References

• Original: J:80821 Foster BA, et al., Enforced expression of FGF-7 promotes epithelial hyperplasia whereas a dominant negative FGFR2iiib promotes the emergence of neuroendocrine phenotype in prostate glands of transgenic mice. Differentiation. 2002 Dec;70(9-10):624-32
• All: 1 reference(s)