Tg(Lck-cre)1Cwi
Transgene Detail

Summary

• Symbol: Tg(Lck-cre)1Cwi
• Name: transgene insertion 1, Christopher B Wilson
• MGI ID: MGI:2448686
• Synonyms: cwLckCre, iLck^cre, lck-cre, lckCre, Lck-Cre, Lck-Cre⁺, plck-cre, pLck-cre
• Transgene: Tg(Lck-cre)1Cwi Location: unknown
• Alliance: Tg(Lck-cre)1Cwi page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Lck-cre)1Cwi expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Lck

• Mutation details: This transgene expresses Cre recombinase under the control of the Lck promoter, active in T cells during development. (J:73127)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lck (species not specified) Summary of all recombinase alleles driven by Lck. Comparative matrix view of recombinase activities

Disease models

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Lck-cre)1Cwi

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available

References

• Original: J:73127 Lee PP, et al., A critical role for dnmt1 and DNA methylation in T cell development, function, and survival. Immunity. 2001 Nov;15(5):763-74
• All: 197 reference(s)