Car8^wdl
Spontaneous Allele Detail

Summary

• Symbol: Car8^wdl
• Name: carbonic anhydrase 8; waddles
• MGI ID: MGI:2449035
• Synonyms: rig, rigoletto
• Gene: Car8 Location: Chr4:8143362-8239041 bp, - strand Genetic Position: Chr4, 3.53 cM
• Alliance: Car8^wdl page

Mutation origin

• Strain of Origin: C57BLKS/J

Mutation description

• Allele Type: Spontaneous (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Mutant mice contain a 19-nucleotide deletion, 15 of which are flanked by two AAGG motifs. Car8 transcript is absent in homozygous mice, suggesting that this is a null mutation. (J:103673)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Car8 Mutation: 23 strains or lines available

Notes

This mutation arose at The Jackson Laboratory.

References

• Original: J:81344 Harris BS, et al., A new mutation, waddles (wdl), on mouse Chromosome 4. Mouse Mutant Resources Web Site, The Jackson Laboratory, Bar Harbor, Maine. MGI Direct Data Submission. 2003
• All: 13 reference(s)