Gt(ROSA)26Sor^tm2(ECFP)Cos
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm2(ECFP)Cos
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Frank Costantini
• MGI ID: MGI:2449039
• Synonyms: R26R^CFP, R26R-ECFP, ROSA-stop^flox-CFP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm2(ECFP)Cos page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:80963
• Parent Cell Line: JM-1 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

Allele Type: Targeted (Conditional ready, Reporter) Mutation: Insertion Mutation details: A construct containing a floxed PGK-neo cassette and an enhanced cyan fluorescent protein (ECFP) gene was inserted into the Gt(ROSA)26Sor locus via homologous recombination. The floxed neo cassette contains a strong tpA stop sequence which prevents the transcription of ECFP. (J:80963)

Generation of Gt(ROSA)26Sor^tm1(EYFP)Cos or Gt(ROSA)26Sor^tm2(ECFP)Cos.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:80963 Srinivas S, et al., Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol. 2001;1(1):4
• All: 17 reference(s)