Ldha^l7R2-1R
Chemically induced Allele Detail

Summary

• Symbol: Ldha^l7R2-1R
• Name: lactate dehydrogenase A; 1 Oak Ridge
• MGI ID: MGI:2449589
• Synonyms: 1318SJ
• Gene: Ldha Location: Chr7:46491698-46505051 bp, + strand Genetic Position: Chr7, 30.6 cM
• Alliance: Ldha^l7R2-1R page

Mutation origin

• Strain of Origin: BJR

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This phenotypic mutant was identified in an ENU mutagenesis screen at The Oak Ridge National Laboratory. A T-to-A mutation in exon 5 results in a leucine to glutamine substitution (L190Q) in the encoded protein. (J:101682)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ldha Mutation: 35 strains or lines available

References

• Original: J:73982 Rinchik EM, et al., Functional annotation of mammalian genomic DNA sequence by chemical mutagenesis: A fine-structure genetic mutation map of a 1- to 2-cM segment of mouse chromosome 7 corresponding to human chromosome 11p14-p15. Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):844-9
• All: 2 reference(s)