Hikeshi^1R
Chemically induced Allele Detail

Summary

• Symbol: Hikeshi^1R
• Name: heat shock protein nuclear import factor; mutation 1, Oak Ridge
• MGI ID: MGI:2449650
• Synonyms: 4234SB, l(7)6Rn^4234SB, l7Rn6^1R, l7Rn6^4234SB
• Gene: Hikeshi Location: Chr7:89567893-89590446 bp, - strand Genetic Position: Chr7, 50.4 cM, cytoband E1
• Alliance: Hikeshi^1R page

Mutation origin

• Strain of Origin: BALB/cRl

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This phenotypic mutant was identified in an ENU mutagenesis screen at The Oak Ridge National Laboratory. A T-to-A transversion was detected at thymine 543 of the coding region. This transversion encompasses the third nucleotide of codon 181 (TAT/TAA) and substitutes a tyrosine residue with a stop codon (Y181X), truncating the carboxy-terminal 17 amino acids of the encoded protein. (J:105164)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	29 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hikeshi Mutation: 30 strains or lines available

Notes

Genbank ID for this allele: DQ196316

References

• Original: J:12917 Rinchik EM, et al., N-ethyl-N-nitrosourea-induced prenatally lethal mutations define at least two complementation groups within the embryonic ectoderm development (eed) locus in mouse chromosome 7. Mamm Genome. 1993;4(7):349-53
• All: 3 reference(s)