Tg(APOE-cre)VITew
Transgene Detail

Summary

• Symbol: Tg(APOE-cre)VITew
• Name: transgene insertion VI, Thomas E Willnow
• MGI ID: MGI:2449766
• Synonyms: ApoE-CreVI
• Transgene: Tg(APOE-cre)VITew Location: unknown
• Alliance: Tg(APOE-cre)VITew page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(APOE-cre)VITew expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  APOE (348)

  Apoe	(MGI:88057)

• Mutation details: A 3.0 kb fragment of the human APOE promoter was adjoined to NLS-cre which was followed by a 0.2 kb APOE polyadenylation signal. Expression was driven in the proximal and distal tubuli of the renal cortex. (J:81496)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	APOE (human) Summary of all recombinase alleles driven by APOE. Comparative matrix view of recombinase activities Alliance human APOE gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:81496 Leheste JR, et al., Hypocalcemia and osteopathy in mice with kidney-specific megalin gene defect. FASEB J. 2003 Feb;17(2):247-9
• All: 13 reference(s)