Tg(KRT14-Pgf)1Odo
Transgene Detail

Summary

• Symbol: Tg(KRT14-Pgf)1Odo
• Name: transgene insertion 1, Teresa Odorisio
• MGI ID: MGI:2450137
• Synonyms: K14-PlGF
• Transgene: Tg(KRT14-Pgf)1Odo Location: unknown
• Alliance: Tg(KRT14-Pgf)1Odo page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT14-Pgf)1Odo expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Pgf (MGI:105095)

• Mutation details: The human KRT14 promoter was used to overexpress the mouse PGF (nucleotides 119-595) in skin cells. Expression of the transgene in epidermal cells was confirmed by in situ hybridization analysis of skin sections, and by Western blot analysis of skin lysates. (J:77722)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

The 2 highest expressing transgenic lines, carrying 10-12 copies of the transgene, were used for analysis.

References

• Original: J:77722 Odorisio T, et al., Mice overexpressing placenta growth factor exhibit increased vascularization and vessel permeability. J Cell Sci. 2002 Jun 15;115(Pt 12):2559-67
• All: 3 reference(s)