Zfx^tm1Dcp
Targeted Allele Detail

Summary

• Symbol: Zfx^tm1Dcp
• Name: zinc finger protein X-linked; targeted mutation 1, David C Page
• MGI ID: MGI:2450147
• Gene: Zfx Location: ChrX:93118237-93167308 bp, - strand Genetic Position: ChrX, 41.48 cM, cytoband D
• Alliance: Zfx^tm1Dcp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:41131
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 7 through 10 were replaced by a neomycin selection cassette inserted by homologous recombination. The deleted region encoded half of the acidic domain and the nuclear localiztion signal. (J:41131)

Expression

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfx Mutation: 33 strains or lines available

References

• Original: J:41131 Luoh SW, et al., Zfx mutation results in small animal size and reduced germ cell number in male and female mice. Development. 1997 Jun;124(11):2275-84
• All: 5 reference(s)