Mtnr1b^tm1Drw
Targeted Allele Detail

Summary

• Symbol: Mtnr1b^tm1Drw
• Name: melatonin receptor 1B; targeted mutation 1, David R Weaver
• MGI ID: MGI:2450159
• Synonyms: MT2 KO
• Gene: Mtnr1b Location: Chr9:15773910-15785852 bp, - strand Genetic Position: Chr9, 5.15 cM
• Alliance: Mtnr1b^tm1Drw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:81644
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Exon 1 was disrupted by the insertion of a PGK-neo cassette. (J:81644)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mtnr1b Mutation: 33 strains or lines available

References

• Original: J:81644 Jin X, et al., Targeted disruption of the mouse Mel(1b) melatonin receptor. Mol Cell Biol. 2003 Feb;23(3):1054-60
• All: 23 reference(s)