Tg(Dspp-cre)1Kul
Transgene Detail

Summary

• Symbol: Tg(Dspp-cre)1Kul
• Name: transgene insertion 1, Ashok B Kulkarni
• MGI ID: MGI:2450281
• Synonyms: Dspp-Cre
• Transgene: Tg(Dspp-cre)1Kul Location: unknown
• Alliance: Tg(Dspp-cre)1Kul page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Dspp-cre)1Kul expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Dspp (MGI:109172)

• Mutation details: 6 kb of mouse Dspp promoter sequences were used to drive expression of cre recombinase in teeth. Transgene expression in odontoblasts was confirmed by immunohistochemical analysis of cross sections from 30 old transgenic mice. (J:81653)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Dspp (mouse) Summary of all recombinase alleles driven by Dspp. Comparative matrix view of recombinase activities Alliance mouse Dspp gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

Notes

Transgenic line E displayed tooth-specific transgene expression and was used for further characterization and analysis.

References

• Original: J:81653 Sreenath TL, et al., Odontoblast-specific expression of cre recombinase successfully deletes gene segments flanked by loxp sites in mouse teeth. Genesis. 2003 Feb;35(2):94-9
• All: 2 reference(s)