Pdzk1^tm1Oko
Targeted Allele Detail

Summary

• Symbol: Pdzk1^tm1Oko
• Name: PDZ domain containing 1; targeted mutation 1, Oliver Kocher
• MGI ID: MGI:2450706
• Synonyms: Pdzk1-
• Gene: Pdzk1 Location: Chr3:96736772-96778242 bp, + strand Genetic Position: Chr3, 42.0 cM
• Alliance: Pdzk1^tm1Oko page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:81814
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: The gene was disrupted by insertion of a neomycin resistance cassette via homologous recombination. Absence of gene expression homozygous mutant kidneys was confirmed by Western blot analysis. (J:81814)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdzk1 Mutation: 26 strains or lines available

References

• Original: J:81814 Kocher O, et al., Targeted Disruption of the PDZK1 Gene by Homologous Recombination. Mol Cell Biol. 2003 Feb;23(4):1175-80
• All: 16 reference(s)