Bmp15^tm1Zuk
Targeted Allele Detail

Summary

• Symbol: Bmp15^tm1Zuk
• Name: bone morphogenetic protein 15; targeted mutation 1, Martin M Matzuk
• MGI ID: MGI:2450734
• Synonyms: Bmp15^-, X^Bmp15tm1
• Gene: Bmp15 Location: ChrX:6226161-6232775 bp, - strand Genetic Position: ChrX, 2.81 cM
• Alliance: Bmp15^tm1Zuk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:69611
• Parent Cell Line: AB2.1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced with a PGK-hprt cassette inserted by homologous recombination. The deleted region encoded 159 carboxy terminal amino acids. (J:69611)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bmp15 Mutation: 3 strains or lines available

References

• Original: J:69611 Yan C, et al., Synergistic roles of bone morphogenetic protein 15 and growth differentiation factor 9 in ovarian function. Mol Endocrinol. 2001 Jun;15(6):854-66
• All: 8 reference(s)