Cx3cr1^tm1Ifc
Targeted Allele Detail

Summary

• Symbol: Cx3cr1^tm1Ifc
• Name: C-X3-C motif chemokine receptor 1; targeted mutation 1, Israel F Charo
• MGI ID: MGI:2450885
• Synonyms: CX3CR1-
• Gene: Cx3cr1 Location: Chr9:119877749-119897362 bp, - strand Genetic Position: Chr9, 71.37 cM
• Alliance: Cx3cr1^tm1Ifc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82033
• Parent Cell Line: RF8 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire coding region of the gene was replaced with a floxed neomycin resistance cassette via homologous recombination. (J:82033)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cx3cr1 Mutation: 45 strains or lines available

References

• Original: J:82033 Haskell CA, et al., Targeted deletion of CX(3)CR1 reveals a role for fractalkine in cardiac allograft rejection. J Clin Invest. 2001 Sep;108(5):679-88
• All: 10 reference(s)