Tg(Prrx1-cre)1Cjt
Transgene Detail

Summary

• Symbol: Tg(Prrx1-cre)1Cjt
• Name: transgene insertion 1, Clifford J Tabin
• MGI ID: MGI:2450929
• Synonyms: Prx1-cre, Prx1^cre, Prx-1 Cre, Prx1Cre, Prx-cre, Tg[Prx1-cre]1Cjt
• Transgene: Tg(Prrx1-cre)1Cjt Location: unknown
• Alliance: Tg(Prrx1-cre)1Cjt page

Transgene origin

• Strain of Origin: (C57BL/6J x SJL/J)F2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Prrx1-cre)1Cjt expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Prrx1

• Mutation details: This transgene expresses Cre recombinase under the control of a Prrx1 derived enhancer. This transgene is expressed in the early limb bud mesenchyme and in a subset of craniofacial mesenchyme. A germline Cre recombinase activity was observed in female, but not in male, as partially penetrant trait depending on the particular gene flanked by loxP sites. (J:77872)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Prrx1 (species not specified) Summary of all recombinase alleles driven by Prrx1. Comparative matrix view of recombinase activities

Disease models

Expression

In Mice Carrying this Mutation:

104974 assay results 24 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Prrx1-cre)1Cjt

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:77872 Logan M, et al., Expression of Cre recombinase in the developing mouse limb bud driven by a Prxl enhancer. Genesis. 2002 Jun;33(2):77-80
• All: 494 reference(s)