Pelo^tm1Imad
Targeted Allele Detail

Summary

• Symbol: Pelo^tm1Imad
• Name: pelota mRNA surveillance and ribosome rescue factor; targeted mutation 1, Ibrahim M Adham
• MGI ID: MGI:2450933
• Synonyms: Pelo^-
• Gene: Pelo Location: Chr13:115224891-115226694 bp, - strand Genetic Position: Chr13, 64.61 cM
• Alliance: Pelo^tm1Imad page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:81781
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 3.2 kb fragment containing exons 2 and 3 was deleted by the insertion of a neomycin selection cassette. (J:81781)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pelo Mutation: 15 strains or lines available

References

• Original: J:81781 Adham IM, et al., Disruption of the pelota gene causes early embryonic lethality and defects in cell cycle progression. Mol Cell Biol. 2003 Feb;23(4):1470-6
• All: 3 reference(s)