Gemin2^tm1Msd
Targeted Allele Detail

Summary

• Symbol: Gemin2^tm1Msd
• Name: gem nuclear organelle associated protein 2; targeted mutation 1, Michael Sendtner
• MGI ID: MGI:2451054
• Synonyms: Gemin2^-
• Gene: Gemin2 Location: Chr12:59060179-59075256 bp, + strand Genetic Position: Chr12, 25.99 cM, cytoband C2
• Alliance: Gemin2^tm1Msd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:81784
• Parent Cell Line: E14TG2aIV (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The gene was disrupted by replacement of exon 1 with an EBFP-neo cassette via homologous recombination. (J:81784)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gemin2 Mutation: 10 strains or lines available

References

• Original: J:81784 Jablonka S, et al., Gene targeting of Gemin2 in mice reveals a correlation between defects in the biogenesis of U snRNPs and motoneuron cell death. Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):10126-31
• All: 2 reference(s)