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Mertknmf12
Chemically induced Allele Detail
Summary
Symbol: Mertknmf12
Name: MER proto-oncogene tyrosine kinase; neuroscience mutagenesis facility, 12
MGI ID: MGI:2651819
Gene: Mertk  Location: Chr2:128540876-128644814 bp, + strand  Genetic Position: Chr2, 62.63 cM
Alliance: Mertknmf12 page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsENU induced a A to G missense mutation at base pair 2147 resulting in a histidine to arginine substitution at amino acid position 716. (J:82238, J:175587)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mertk Mutation:  65 strains or lines available
References
Original:  J:82238 JAX Neuroscience Mutagenesis Facility, Heritable mouse mutants from JAX NMF ENU Mutagenesis Program. MGI Direct Data Submission. 2003;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory