Plcb4^tm1Hssh
Targeted Allele Detail

Summary

• Symbol: Plcb4^tm1Hssh
• Name: phospholipase C, beta 4; targeted mutation 1, Hee-Sup Shin
• MGI ID: MGI:2652541
• Synonyms: PLCBeta4^-
• Gene: Plcb4 Location: Chr2:135500931-135856513 bp, + strand Genetic Position: Chr2, 66.64 cM
• Alliance: Plcb4^tm1Hssh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:43077
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• The endogenous gene was disrupted by the insertion of a neomycin selection cassette. (J:43077)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plcb4 Mutation: 130 strains or lines available

References

• Original: J:43077 Kim D, et al., Phospholipase C isozymes selectively couple to specific neurotransmitter receptors. Nature. 1997 Sep 18;389(6648):290-3
• All: 10 reference(s)