Tg(KRT14-cre)1Cgn
Transgene Detail

Summary

• Symbol: Tg(KRT14-cre)1Cgn
• Name: transgene insertion 1, University of Cologne
• MGI ID: MGI:2652655
• Synonyms: K14-Cre, K14Cre#47
• Transgene: Tg(KRT14-cre)1Cgn Location: unknown
• Alliance: Tg(KRT14-cre)1Cgn page

Transgene origin

• Strain of Origin: C57BL/6 X (C57BL/6 x DBA/2)F2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(KRT14-cre)1Cgn expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  KRT14 (3861)

  Krt14

  (MGI:96688)

• Mutation details: This transgene expresses Cre recombinase under the control of a human keratin 14 promoter. This transgene is expressed in the epidermis, hair follicles and the epithelium of the tongue. Three lines were generated (K14Cre#47, K14Cre#44, and K14Cre#105) which all show maternal cre mediated deletion. (J:77233, J:89717)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	KRT14 (human) Summary of all recombinase alleles driven by KRT14. Comparative matrix view of recombinase activities Alliance human KRT14 gene page

Disease models

Expression

In Mice Carrying this Mutation:

216 assay results 5 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:89717 Hafner M, et al., Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyte-expressed protein. Genesis. 2004 Apr;38(4):176-81
• All: 90 reference(s)