Cd5l^tm1Nto
Targeted Allele Detail

Summary

• Symbol: Cd5l^tm1Nto
• Name: CD5 antigen-like; targeted mutation 1, Makoto Naito
• MGI ID: MGI:2653296
• Synonyms: AIM^-
• Gene: Cd5l Location: Chr3:87265188-87278380 bp, + strand Genetic Position: Chr3, 38.19 cM
• Alliance: Cd5l^tm1Nto page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82352
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: Exon 3 was disrupted by a neomycin selection cassette inserted by homologous recombination. The disrupted region encoded the second scavenger receptor cysteine-rich (SRCR) domain. (J:52195, J:82352)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd5l Mutation: 30 strains or lines available

References

• Original: J:82352 Kuwata K, et al., AIM inhibits apoptosis of T cells and NKT cells in Corynebacterium-induced granuloma formation in mice. Am J Pathol. 2003 Mar;162(3):837-47
• All: 15 reference(s)