n-TUtca2^tm1Dhat
Targeted Allele Detail

Summary

• Symbol: n-TUtca2^tm1Dhat
• Name: nuclear encoded tRNA selenocysteine 2 (anticodon TCA); targeted mutation 1, Dolph L Hatfield
• MGI ID: MGI:2653318
• Synonyms: Trsp^fl
• Gene: n-TUtca2 Location: Chr7:19035169-19035255 bp, + strand Genetic Position: Chr7, 9.56 cM
• Alliance: n-TUtca2^tm1Dhat page

Small size, hypomorphic ears and shortened snout in n-TUtca2^tm1Dhat/n-TUtca2^tm1Dhat Tg(Col2a1-cre)1Bhr/0 mice

Show the 6 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82321
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The endogenous tRNA coding region was flanked by single loxP sites. (J:82321)

Disease models

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	18 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any n-TUtca2 Mutation: 2 strains or lines available

References

• Original: J:82321 Kumaraswamy E, et al., Selective removal of the selenocysteine tRNA [Ser]Sec gene (Trsp) in mouse mammary epithelium. Mol Cell Biol. 2003 Mar;23(5):1477-88
• All: 27 reference(s)