Lipg^tm1Chan
Targeted Allele Detail

Summary

• Symbol: Lipg^tm1Chan
• Name: lipase, endothelial; targeted mutation 1, Lawrence Chan
• MGI ID: MGI:2653887
• Synonyms: EL-
• Gene: Lipg Location: Chr18:75072393-75094334 bp, - strand Genetic Position: Chr18, 50.94 cM, cytoband E2
• Alliance: Lipg^tm1Chan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82390
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Disruption caused by insertion of vector
• Exon 2 was replaced with a neomycin selection cassette inserted by homologous recombination. (J:82390)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lipg Mutation: 29 strains or lines available

References

• Original: J:82390 Ma K, et al., Endothelial lipase is a major genetic determinant for high-density lipoprotein concentration, structure, and metabolism. Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2748-53
• All: 3 reference(s)