Foxh1^tm1.1Hmd
Targeted Allele Detail

Summary

• Symbol: Foxh1^tm1.1Hmd
• Name: forkhead box H1; targeted mutation 1.1, Hiroshi Hamada
• MGI ID: MGI:2654232
• Synonyms: Foxh1^-
• Gene: Foxh1 Location: Chr15:76552425-76554148 bp, - strand Genetic Position: Chr15, 36.24 cM
• Alliance: Foxh1^tm1.1Hmd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:69593
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele is derived from Foxh1^tm1Hmd. Mutant animals were bred to cre-expressing line Tg(ACTB-cre)13Miya to delete exon 2 and the neo cassette. Homozygous mutant embryos did not express gene transcripts as determined by Northern blot and RT-PCR analysis. (J:69593)

Expression

In Mice Carrying this Mutation:	49 assay results
In Structures Affected by this Mutation:	10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Foxh1 Mutation: 34 strains or lines available

References

• Original: J:69593 Yamamoto M, et al., The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse. Genes Dev. 2001 May 15;15(10):1242-56
• All: 5 reference(s)