Mab21l1^tm1Nao
Targeted Allele Detail

Summary

• Symbol: Mab21l1^tm1Nao
• Name: mab-21-like 1; targeted mutation 1, Naoki Takahashi
• MGI ID: MGI:2654257
• Synonyms: Mab21l1^-
• Gene: Mab21l1 Location: Chr3:55689931-55692422 bp, + strand Genetic Position: Chr3, 26.65 cM, cytoband E3-F1
• Alliance: Mab21l1^tm1Nao page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82312
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire gene coding region was replaced with a neomycin resistance cassette via homologous recombination. Absence of gene expression in homozygous mutants was confirmed by whole mount in situ hybridization analysis of E10.5 homozygous mutant embryos. (J:82312)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	15 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mab21l1 Mutation: 15 strains or lines available

References

• Original: J:82312 Yamada R, et al., Cell-autonomous involvement of Mab21l1 is essential for lens placode development. Development. 2003 May;130(9):1759-70
• All: 3 reference(s)