Cxxc1^tm1Skk
Targeted Allele Detail

Summary

• Symbol: Cxxc1^tm1Skk
• Name: CXXC finger protein 1; targeted mutation 1, David G Skalnik
• MGI ID: MGI:2654854
• Synonyms: CGBP-null
• Gene: Cxxc1 Location: Chr18:74349283-74354564 bp, + strand Genetic Position: Chr18, 50.7 cM
• Alliance: Cxxc1^tm1Skk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:72634
• Parent Cell Line: CCE916 (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin selection cassette replaced the entire coding region of the gene, including 5 kb of upstream sequence. (J:72634)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cxxc1 Mutation: 28 strains or lines available

References

• Original: J:72634 Carlone DL, et al., Cpg binding protein is crucial for early embryonic development. Mol Cell Biol. 2001 Nov;21(22):7601-6
• All: 3 reference(s)