Tg(Rr443-Lefty1,-lacZ)36Hmd
Transgene Detail

Summary

• Symbol: Tg(Rr443-Lefty1,-lacZ)36Hmd
• Name: transgene insertion 36, Hiroshi Hamada
• MGI ID: MGI:2654946
• Synonyms: Tg(Leftb)36Hmd, Tg(NDE-hsp-Nodal,lacZ)36Hmd
• Transgene: Tg(Rr443-Lefty1,-lacZ)36Hmd Location: unknown
• Alliance: Tg(Rr443-Lefty1,-lacZ)36Hmd page

Transgene origin

• Strain of Origin: C57BL/6Cr

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Rr443-Lefty1,-lacZ)36Hmd expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Lefty1 (MGI:107405)

• Tg(Rr443-Lefty1,-lacZ)36Hmd expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Nodal (MGI:97359)

• Mutation details: The transgene consists of 2 tandem copies of the Nodal node-specific enhancer (NDE) linked to the heat shock promoter, Leftb cDNA, and an IRES-lacZ sequence. (J:82703)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:82703 Saijoh Y, et al., Left-right patterning of the mouse lateral plate requires nodal produced in the node. Dev Biol. 2003 Apr 1;256(1):160-72
• All: 1 reference(s)