Tg(Krt1-14-GLI)1Oro
Transgene Detail

Summary

• Symbol: Tg(Krt1-14-GLI)1Oro
• Name: transgene insertion 1, Anthony E Oro
• MGI ID: MGI:2655200
• Synonyms: K14-Gli
• Transgene: Tg(Krt1-14-GLI)1Oro Location: unknown
• Alliance: Tg(Krt1-14-GLI)1Oro page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Krt1-14-GLI)1Oro expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  GLI1 (2735)

  Gli1	(MGI:95727)

• The transgene is composed of a human GLI cDNA and a keratin 14 promoter, active in the skin. (J:82653)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Three founder animals were created which displayed similar phenotypes. Founder K14 Gli353 was used for analysis.

References

• Original: J:82653 Oro AE, et al., Hair cycle regulation of Hedgehog signal reception. Dev Biol. 2003 Mar 15;255(2):238-48
• All: 1 reference(s)