H19^tm1.1Sriv
Targeted Allele Detail

Summary

• Symbol: H19^tm1.1Sriv
• Name: H19, imprinted maternally expressed transcript; targeted mutation 1.1, Madhulika Srivastava
• MGI ID: MGI:2655221
• Synonyms: H19^{delta ex1}
• Gene: H19 Location: Chr7:142129267-142131883 bp, - strand Genetic Position: Chr7, 87.97 cM
• Alliance: H19^tm1.1Sriv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82595
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The floxed region encompassing neo and exon 1 was deleted by the expression of cre recombinase in the germline. (J:82595)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any H19 Mutation: 12 strains or lines available

References

• Original: J:82595 Srivastava M, et al., Imprint control element-mediated secondary methylation imprints at the Igf2/H19 locus. J Biol Chem. 2003 Feb 21;278(8):5977-83
• All: 6 reference(s)