Grid2^ho-Nancy
Spontaneous Allele Detail

Summary

• Symbol: Grid2^ho-Nancy
• Name: glutamate receptor, ionotropic, delta 2; hotfoot Nancy
• MGI ID: MGI:2655335
• Gene: Grid2 Location: Chr6:63232860-64681307 bp, + strand Genetic Position: Chr6, 29.77 cM
• Alliance: Grid2^ho-Nancy page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: This allele contains a 984 bp deletion from position 1246-2193 (amino acids 416-732) of the coding sequence. The deletion does not alter the reading frame of the gene. Truncated transcripts were detected by Northern blot analysis, but Western blot failed to detect protein product.
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Grid2 Mutation: 85 strains or lines available

References

• Original: J:82709 Guastavino JM, et al., Hot-foot murine mutation: behavioral effects and neuroanatomical alterations. Brain Res. 1990 Jul 23;523(2):199-210
• All: 9 reference(s)