Ilk^tm1Ref
Targeted Allele Detail

Summary

• Symbol: Ilk^tm1Ref
• Name: integrin linked kinase; targeted mutation 1, Reinhard Fassler
• MGI ID: MGI:2655773
• Synonyms: Ilk^lacZ
• Gene: Ilk Location: Chr7:105385799-105392132 bp, + strand Genetic Position: Chr7, 55.97 cM, cytoband E1
• Alliance: Ilk^tm1Ref page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82761
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The gene was disrupted by replacement of exon 2 with a lacZ-PGK-neo cassette via homologous recombination. (J:82761)

Expression

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ilk Mutation: 18 strains or lines available

References

• Original: J:82761 Sakai T, et al., Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation. Genes Dev. 2003 Apr 1;17(7):926-40
• All: 2 reference(s)