Polq^chaos1
Chemically induced Allele Detail

Summary

• Symbol: Polq^chaos1
• Name: polymerase (DNA directed), theta; chromosome abberation occurring spontaneously 1
• MGI ID: MGI:2656007
• Gene: Polq Location: Chr16:36832148-36915779 bp, + strand Genetic Position: Chr16, 26.32 cM, cytoband B4
• Alliance: Polq^chaos1 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation in the chaos1 mouse was identified as a T to C substitution at nucleotide 5794 in the coding region of exon 19. The mutation results in a serine to proline change at amino acid residue 1932. (J:82700)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Polq Mutation: 126 strains or lines available

References

• Original: J:82700 Shima N, et al., Phenotype-based identification of mouse chromosome instability mutants. Genetics. 2003 Mar;163(3):1031-40
• All: 2 reference(s)