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Pdgfratm7Sor
Targeted Allele Detail
Summary
Symbol: Pdgfratm7Sor
Name: platelet derived growth factor receptor, alpha polypeptide; targeted mutation 7, Philippe Soriano
MGI ID: MGI:2656148
Synonyms: alphaF7
Gene: Pdgfra  Location: Chr5:75312953-75358876 bp, + strand  Genetic Position: Chr5, 39.55 cM
Alliance: Pdgfratm7Sor page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:73817
Parent Cell Line:  AK7 (ES Cell)
Strain of Origin:  129S4/SvJaeSor
Mutation
description
Allele Type:    Targeted (Hypomorph, Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA cDNA encoding a mutated receptor consisting of point mutations encoding the tyrosines at codons 572/574, 720, 731/742, 988 and 1018 was targeted into the Pdgfra locus. (J:73817)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pdgfra Mutation:  88 strains or lines available
References
Original:  J:73817 Klinghoffer RA, et al., An allelic series at the PDGFalphaR locus indicates unequal contributions of distinct signaling pathways during development. Dev Cell. 2002 Jan;2(1):103-13
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory