Cyp27b1^tm1.1Star
Targeted Allele Detail

Summary

• Symbol: Cyp27b1^tm1.1Star
• Name: cytochrome P450, family 27, subfamily b, polypeptide 1; targeted mutation 1.1, Rene St-Arnaud
• MGI ID: MGI:2656261
• Gene: Cyp27b1 Location: Chr10:126884119-126888875 bp, + strand Genetic Position: Chr10, 74.5 cM
• Alliance: Cyp27b1^tm1.1Star page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82529
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites that flank exon 8 were inserted by homologous recombination. (J:82529)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cyp27b1 Mutation: 33 strains or lines available

References

• Original: J:82529 St-Arnaud R, et al., Conventional and tissue-specific inactivation of the 25-hydroxyvitamin D-1alpha-hydroxylase (CYP27B1). J Cell Biochem. 2003;88(2):245-51
• All: 7 reference(s)